|
1-5 of 5 messages
|
Page 1 of 1
|
|
RE: frog toxins
|
Reply
|
|
by paleoherp on July 31, 2005
|
Mail this to a friend!
|
A lot of toxins or relativly low molecular weight have been found in anurans although in the fire bellied toad its quite a high molecular weight . Bradykinin ( i think is in bee venom aswell ) caerulin , leptodactylin , physalaemin , phyllokinin , sauvagine and serotonin have all been found in anurans .Bufonids posses numerous bufodienolides which are cardiotoxic steroids , from the toads Atelopus the toxins are known as zeteckotoxins and chiriquitoxin .
Then of course you get the dendrobatid frogs and especially phyllobates have extremally toxic steroidal alkaloides in the skin . Batrachotoxins are among the most potent natrually occuring non protien toxins. These compounds selectivly increase the permeability of the outer membranes of nerve and muscle fibres. Batrachotoxin prevents the normal closing of sodium channels in the cell membranes with the result that cells become depolarized because of massive infuxes of sodium . phyllobates terribilis has enough toxin to kill about 20 thousand 20 - gram mice . Other poison frogs have a more simple structure toxin such as histroconotoxins and pumiliotoxins.
anyway hope this helps
shaun
|
| |
|
RE: frog toxins
|
Reply
|
|
by Phobos on July 31, 2005
|
Mail this to a friend!
|
Well done mate!
Is there anything known on how these toxins are concentrated & excreated by the frogs skin? WC frog can be "detoxed" by feeding captive prey types, fruit flys for instance.
Cheers!
Al
|
| |
|
RE: frog toxins
|
Reply
|
|
by BGF on July 31, 2005
|
Mail this to a friend!
|
Here's a link to a page on my site on frog neurotoxins
http://www.venomdoc.com/amphibian_neurotoxin.html
Cheers
B
|
| |
|
Email Subscription
You are not subscribed to this topic.
Subscribe!
My Subscriptions
Subscriptions Help
Check our help page for help using
, or send questions, comments, or suggestions to the
Manager.
|
