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Eastern Coral snake keepers ALERT
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by Phobos on October 24, 2005
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Yesterdays eye opener came from a study at the Texas A&M Natural Toxins Research Center.
They demonstrated that Wyeth Coral Antivenom had NO neutralizing effect of the venom of Eastern Coral Snake!!!! YIKES!!!! They tested the Bioclone & Costa Rican also and they were effective against M. fulvus and M. tener
Al
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RE: Eastern Coral snake keepers ALERT
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by Cro on October 24, 2005
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Al: If the Wyeth Coral Antivenom does not work, what has caused the recovery of people bitten by Eastern Coral Snakes who were given this Antivenom?
One of my friends was bitten by a Eastern Coral Snake back in the late 70s, and recieved the Wyeth product, and recovered.
Have they changed what type of Coral Snakes that are milked to produce the Wyeth Antivenom over the years?
See if you can find out more details.
Best Regards JohnZ
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RE: Eastern Coral snake keepers ALERT
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by Phobos on October 24, 2005
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This was a hot point of discussion by everyone there. These tests were repeated many times, results published in a real scientific journal.
The MD's feel that hospitals give the serum BEFORE symptoms appear with Coral snake envenomation. Hence maybe drybites or mild envenomation. They were treating no real envenomation. Could have been a bad lot of serum...who knows.
Long before this paper was presented Dr. Gennaro told the group that the lab procuring venom for the horse innoculation part of the process killed off the collection of Fulvus he had given them for this purpose. The venom lab replaced them with a Columbian species of Coral, so Wyeth could have been producing A/V for the wrong species for years..
A hole bunch if eye brows were raised at this discovery.
Al
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RE: Eastern Coral snake keepers ALERT
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by Cro on October 24, 2005
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Al: I would be willing to bet that fulvius and tenere venom was used in AV by Wyeth many years ago, then eventually replaced with the South & Central American coral snakes venom.
The friend who was bitten had severe symptoms and was kept alive on a resperator until the AV arrived. From what I remember, it took a couple of hours for them to find the AV. Not very likely his was a dry or light bite. This was not long after the AV was first developed, and it was not readily available.
Today, he still has some neurlogical problems that he associates with damage the venom did to his system.
After you get back, can you post a link to the Texas research article?
Best Regards
JohnZ
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RE: Eastern Coral snake keepers ALERT
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by Phobos on October 24, 2005
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Hi John:
Dr. Gennaro was the venom pioneer who worked with Wyeth and provided them with the correct venom, so early batches were the real deal!
I have the paper title and will email the author for a PDF because there is not link available. Hang in there, I'll see what I can do.
Al
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RE: Eastern Coral snake keepers ALERT
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by BWSmith on October 27, 2005
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I would also like a copy of this article. It figures that I just picked up a HUGE fulvius this weekend.
B W Smith
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